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It remains unclear whether improvements in depressive symptoms reflect a direct neuropsychotropic effect of GLP1RAs or are secondary to indirect benefits such as improved glycaemic control, weight loss and reductions in systemic inflammation

Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts

Considering the high rate of side-effects, drugs with a more cardiovascular centred mechanism of action are being developed
